Jian Hua
Associate Professor
Jian Hua




Department of Plant Biology
158 Emerson Hall
Cornell University
Ithaca, NY 14853-2703


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Department Profile


Plants monitor and respond to their environment constantly, which is essential for their viability and fitness. The ultimate goal of our research is to understand the molecular mechanisms by which plants perceive environmental signals and integrate signals to regulate their growth and development. We are using Arabidopsis thaliana as a model plant to investigate two distinct but interacting responses, one to temperature variations and one to pathogen invasions.

Research Description

Our first research focus is on molecular genetics of temperature sensing and signaling. The goal is to genetically and molecularly dissect temperature responses at the non-extreme range and to isolate essential genes for these responses. Our second research focus is on molecular genetics of the repression of defense responses by plant host genes. The goal is to study the molecular mechanisms by which the Arabidopsis BON1 gene represses defense responses.

Selected Publications

  • Yang H, Yang S, Li Y, Hua J. (2007) The Arabidopsis BAP1 and BAP2 genes are general inhibitors of programmed cell death. Plant Physio. 145, 135-46.
  • Li Y, Yang S, Yang H, and Hua J. (2007) The TIR-NB-LRR gene SNC1 isregulated at the transcript level by multiple factors MPMI 20:1449-56.
  • Yang H, Li Y, Hua J. (2006) The small C2 protein BAP1 negatively regulates cell death and defense response in Arabidopsis. Plant J, 48: 238-48.
  • Yang S, Yang H, Grisafi P, Sanchatjate S, Fink GR, Sun Q, Hua J. (2006) The BON/CPN gene family represses cell death and promotes cell growth in Arabidopsis. Plant J, 45:166-79.
  • Yang S, Hua J. (2004) A haplotype-specific Resistance gene regulated by BON1 mediates temperature-dependent growth control. Plant Cell, 16:1060-71
  • Hua J, Grisaffi P, Cheng, SH, Fink GR. (2001) Plant growth homeostasis is controlled by the Arabidopsis BON1 and BAP1 genes. Genes Dev, 15:2263-2272.
  • Hua J, Meyerowitz EM. (1998) Ethylene responses are negatively regulated by a receptor gene family. Cell, 94:261-71
  • Hua J, Sakai H, Chen QG, Nourizadeh S, Bleecker AB, Ecker JR, Meyerowitz EM. (1998) EIN4 and ERS2 are two members of the putative ethylene receptor gene family. Plant Cell, 10:1321-32.
  • Sakai H, Hua J, Chen QG, Chang C, Mderano L, Bleecker AB, Meyerowitz EM. (1998) ETR2 is an ETR1-like gene involved in ethylene signaling in Arabidopsis. PNAS, 95:5812-7.
  • Hua J, Chang C, Sun Q, Meyerowitz EM. (1995) Ethylene insensitivity conferred by Arabidopsis ERS gene. Science, 269:1712-4.