Alon Keinan
Assistant Professor

Alon Keinan

Phone

607-254-1328

Address

Department of Biological Statistics & Computational Biology
102A Weill Hall
Cornell University
Ithaca, NY 14853-2703

Email

Web Sites

Lab Web site

Research Description

My research focuses on how human genetic variation has arisen from evolutionary history, with the goal of bringing this population genetics perspective to medical genetics. My background in computer science and statistics allows me to develop theoretical tools and apply them to large-scale genomic data sets, bridging theoretical population genetics and empirical studies.

Selected Publications

A. Keinan, J. C. Mullikin, N. Patterson, and D. Reich. Accelerated genetic drift on chromosome X during the human dispersal out of Africa. Nature Genetics, 41, 66-70 (2009).

F. Yu, A. Keinan, H. Chen, R. J. Ferland, R. S. Hill, A. A. Mignault, C. A. Walsh, and D. Reich. Detecting natural selection by empirical comparison to random regions of the genome. Human Molecular Genetics, 18, 4853-67 (2009).

A. Keinan, J. C. Mullikin, N. Patterson, and D. Reich. Measurement of the human allele frequency spectrum demonstrates greater genetic drift in East Asians than in Europeans. Nature Genetics, 39, 1251-5 (2007).

G. Ayodo, A. L. Price, A. Keinan, A. Ajwang, M. F. Otieno, A. S. S. Orago, N. Patterson, and D. Reich. Combining evidence of natural selection with association analysis increases power to detect Malaria-resistance variants. American Journal of Human Genetics, 81, 234-242 (2007).

A. Keinan, B. Sandbank, C. C. Hilgetag, I. Meilijson, and E. Ruppin. Axiomatic scalable neurocontroller analysis via the Shapley value. Artificial Life, 12(3), 333-352 (2006).

A. Kaufman*, A. Keinan*, I. Meilijson, M. Kupiec, and E. Ruppin. (*equal contribution) Quantitative analysis of genetic and neuronal multi-perturbation experiments. PLoS Computational Biology, 1(6), 500-506 (2005).

A. Keinan, B. Sandbank, C. C. Hilgetag, I. Meilijson, and E. Ruppin. Fair attribution of functional contribution in artificial and biological networks. Neural Computation, 16(9), 1887-1915 (2004).