Overview

The Field of GG&D enrolls 8-15 new students per year into its Ph.D. program, which has been supported by a National Institutes of Health training grant for nearly 30 years. There are more than 55 faculty in GG&D, half of whom are in the Department of Molecular Biology and Genetics (MBG) with the rest from 15 other departments or units.

Viewed broadly, research by sudents in GG&D seeks to uncover the fundamental genetic, biochemical, developmental, and cell biological principles that govern life. Such research utilizes state-of-the-art tools in genetics, genomics, biochemistry, proteomics, cell biology, computational biology, imaging, nanobiotechnology and a variety of in vivo methods to characterize the mechanisms regulating a wide range of biological phenomena.

All of the 60 faculty have independent laboratories; however, many of their interests overlap, resulting in group collaborations and shared activities. One group of Field members is interested in DNA replication, recombination and repair. Another group focuses on cellular organelle functions including protein secretion, membrane trafficking and signal transduction. A third group studies population genomics. A fourth group focuses on epigenetic and transcriptional regulatory mechanisms. A fifth group is interested in regulation of stem cells and mechanisms that dictate their differentiation. A sixth group studies processes fundamental to reproduction, including gametogenesis, meiosis and fertilization. A seventh group focuses on morphogenesis and cellular behavior during development. Some labs study these processes with a particular interest in diseases such as cancer or pathologies associated with aging and obesity. Others seek to uncover basic biological control mechanisms. Humans and a variety of model organisms are employed including bacteria, yeasts, fruit flies, nematodes, plants, and mice. This list of research topics is not exhaustive but is meant to illustrate the range of our activities and interactions. For more information, follow the link to Faculty and Research.